Leader in HA filler manufacturing

Research & Development

Bio Plus specializes in manufacturing hyaluronic acid filler with world-class MDM technology.

MDM technology consists of three major technologies : MBMT, DMCT and MDAP. 

MBMT® : Micro Bead Monophasic Technology

DMCT® : Divinyl sulfone Multi-Crosslink Technology

MDAP® : Multiple Degree Amphiphilic Purification

Through this high-end technologies, we manufacture the special MDM filler®.

Four benefits of MDM filler

MDM filler features four benefits : High-end, High-Quality, Perfect-safety and high-price.


Born by BioPlus’s 
Patented technology

World – first 

Blocking the source 
of side effects 

Premium class 
of High-Quality

Stages of manufacturing MDM filler


MBMT   : Micro Bead Monophasic Technology

Add Micro Bead to manufacture Mono-Phasic HA filler. And it is adjustable to control the wide range of viscosity according to the purpose of use.

DMCT   : Divinyl sulfone Multi-Crosslink Technology

Completes crosslinking with DVS Multi crosslink to get excellent viscosity and moldability of HA filler.

MDAP   : Multiple Degree Amphiphilic Purification

Apply Multi-Staged Purification Technology to manufacture pure and safe products.